How Does Smoke Affect Cholesterol ?

Smoking tobacco in any form, even cigars, will have the effect of increasing LDL cholesterol and decreasing HDL cholesterol. It also slightly increases triglycerides. This is a triple whammy because it negatively affects all your cholesterol levels. Cholesterol levels have a direct correlation with coronary artery disease also known as atherosclerosis.

Smoking Cause Heart Disease

The current data demonstrate that the ill effects of secondhand smoke result from many components of tobacco smoke. These include carbon monoxide, nicotine, polycyclic aromatic hydrocarbons and others.
The carbon monoxide produced by passive smoking competes with oxygen for binding sites on red blood cells. This reduces the blood's ability to deliver oxygen to the heart and compromises the heart muscle's ability to use oxygen to create adenosine triphosphate. The carbon monoxide also increases the amount of lactate in venous blood. 

What about cigar and pipe smoking? 

People who smoke cigars or pipes seem to have a higher risk of death from coronary heart disease (and possibly stroke), but their risk isn't as great as that of cigarette smokers. This is probably because they're less likely to inhale the smoke. Currently there's very little scientific information on cigar and pipe smoking and cardiovascular disease, especially among young men, who represent the vast majority of cigar users.